Treatment of High-Grade Dysplasia and Early Stage Esophageal Adenocarcinoma with an Endoscope: The Ultimate in Minimally Invasive, Curative Therapy

نویسندگان

  • Wayne L. Hofstetter
  • Marta L. Davila
چکیده

There has been a radical paradigm shift away from esophagectomy as the standard of therapy for highgrade dysplasia and early esophageal cancer. A number of organ-sparing endoscopic procedures including endoscopic resection, radiofrequency ablation and cryoablation are emerging as viable and preferable options for the treatment of early esophageal neoplasia. This review article will discuss ideal candidates for endoscopic therapies, current treatment modalities, clinical and safety outcomes, and specific management recommendations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Neoadjuvant Therapy on Early Complications of Esophageal Cancer Surgery

Introduction: Early diagnosis and appropriate treatment is required in esophageal cancer due to its invasive nature. The aim of this study was to evaluate early post-esophagectomy complications in patients with esophageal cancer who received neoadjuvant chemoradiotherapy (NACR).   Materials and Methods: This randomized clinical trial was carried out between 2009 and 2011. Patients with lower-th...

متن کامل

Changes in health-related quality of life in oesophagogastric cancer patients participating in palliative and curative therapies

Background: Various treatments are used to prolong survival and improve quality of life (QOL). The purpose of this study was to assess the change in QOL scores in patients with Oesophagogastric (OG) cancer undergoing curative intent and palliative therapy.    Methods: This was a mix-designed cohort study with a consecutive sampling of patients with OG cancer who underwent curative or...

متن کامل

Nonsurgical Management of Esophageal Cancer

In the recent past, the incidence of esophageal adenocarcinomas has risen dramatically, whereas the incidence of squamous cell carcinomas has remained relatively steady in the United States (Holmes & Vaughan, 2007). Esophageal adenocarcinoma arises from Barrett’s esophagus with an estimated incidence rate of 0.4-0.7 per 100-patients/year. (Sharma et al., 2004; Thomas et al., 2007). Barrett’s es...

متن کامل

Comparison of laparoscopic inversion esophagectomy and open transhiatal esophagectomy for high-grade dysplasia and stage I esophageal adenocarcinoma.

HYPOTHESIS The perioperative outcomes of laparoscopic inversion esophagectomy (LIE) are comparable to those of open transhiatal esophagectomy (THE), with potential benefits related to the use of minimally invasive techniques. DESIGN Case-control study. SETTING Tertiary care university hospital. PATIENTS AND INTERVENTIONS From July 1, 2003, through March 31, 2008, 21 consecutive patients u...

متن کامل

Endoscopic methods in the treatment of early-stage esophageal cancer

Most patients with early esophageal cancer restricted to the mucosa may be offered endoscopic therapy, which is similarly effective, less invasive and less expensive than esophagectomy. Selection of appropriate relevant treatment and therapy methods should be performed at a specialized center with adequate facilities. The selection of an endoscopic treatment method for high-grade dysplasia and ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014